FACILITY LIST

Manufacturing Equipment

The facility caters for a wide range of GMP-compliant manufacturing processes for active pharmaceutical ingredients and intermediates.
Reaction vessels are available in sizes ranging from small to large quantities, and special reaction vessels (one-pressure reaction, low-temperature reaction, acid-resistant reaction, etc.) are also available, along with a full range of ancillary equipments necessary for post-reaction processing.

  • Kinraku Plant, The first plant

    Reactors
    65～500L(GL/SUS、×5)
    500L~3000L(GL、×8)
    3000L～5000L(GL、×7)
    6000L(SUS、×1)
    Filters
    Top discharge centrifuge　×2
    Dryers
    High vacuum compartment tray dryer　×4
    Micronizers
    Pin mill ×1
    Special manufacturing equipment
    Ultra low temperature reactors (-80℃) 500L、1500L、3000L(SUS、×3)

  • Kinraku Plant, The second, Facilities for development-stage production (Pilot-scale)

    Reactors
    200L、500L、1500L、(GL、×3)
    2000L、3000L(GL、×2)
    500L(HAS、Class-1 pressure vessel(0.98MPa)、×1)
    Filters
    Top discharge centrifuge　×2
    Filter press ×1
    Dryers
    High vacuum compartment tray dryer　×1

  • Kinraku Plant, The second plant, S area

    Reactors
    1000L、2000L(SUS、×2)
    4000L(GL、×1)
    6000L(GL、×1)
    Filters
    Top discharge centrifuge　×2
    Dryers
    High vacuum compartment tray dryer　×1

  • Senboku Plant, The first plant

    Reactors
    300L、500L(GL、×2)
    1500L~3000L(GL、×6)
    5000L(GL、×4)
    2800L、5000L(SUS、×2)
    Filters
    Top discharge centrifuge　×4
    Filter press ×1
    Dryers
    High vacuum compartment tray dryer　×1
    Conical dryer ×1
    Special manufacturing equipment
    High temperature reactors (～200℃) SUS、×1

  • Senboku Plant, The second plant

    Reactors
    1500L~3000L(GL、×7)
    5000L(GL、×3)
    6000L、8000L(GL、×2)
    5000L(HAS、Class-1 pressure vessel(0.98MPa)、×1)
    Filters
    Top discharge centrifuge　×4
    Dryers
    Vibration vacuum dryer ×3
    Micronizers
    Jet Mill ×1、Powermill ×1、Micronizers ×1

  • Senboku Plant, The third plant

    Reactors
    4000L~5000L(GL、×5)
    6000L(GL、×1)
    8000L~10000L(GL、×4)
    3000L(SUS、×1)
    5000L(HAS、Class-1 pressure vessel(0.98MPa)、×1)
    Filters
    Top discharge centrifuge　×3
    Dryers
    Conical dryer ×2

The manufacturing facilities for HPAPI

Highly pharmacologically active substances are substances that exhibit strong pharmacological effects, such as anticancer drugs, but also have harmful effects on the human body.
These substances must be contained in equipments.
We have equipments and a facility that can provide a high level of containment (Category 4 compliant).
The high-containment facility can cater for a variety of reactions and unit operations as in the case of the general product manufacturing facilities.

  • Kinraku Plant, The second plant, Facilities for highly potent active pharmaceutical ingredients (Pilot-scale)

    Reactors
    65L、200L、500L(GL、×3)
    500L(SUS、×1)
    Filters
    Top discharge centrifuge　×1
    Dryers
    Multifunctional Filter/Dryer ×1
    Micronizers
    Jet mill ×1、Pin mill×2

  • Senboku Plant, The third plant, Facilities for highly potent active pharmaceutical ingredients

    Reactors
    1500L(GL、×2)
    3000L、5000L(GL、×2)
    Filters
    Top discharge centrifuge ×1
    Dryers
    Multifunctional Filter/Dryer ×1
    Micronizers
    Jet mill ×1、Pin mill×1

  • Senboku Plant, The fourth plant, Facilities for highly potent active pharmaceutical ingredients

    Reactors
    1500L、3000L(GL、×3)、3000L(SUS ×1)
    5000L(GL、×2)、8000L(GL、×4)
    10000L(GL、×5)
    Filters
    Top discharge centrifuge ×2
    Dryers
    Multifunctional Filter/Dryer ×1
    Conical Dryer ×2
    Micronizers
    Jet mill ×1

GL：Glass-lined、SUS：Stainless-steel

ABOUT HPAPI

DETAIL

  • PHARMACEUTICAL
    BUSINESS

    We provide process development, method development and validation, and manufacturing services for intermediates and APIs (Active Pharmaceutical Ingredients), which have been developed by pharmaceutical companies, academia, and venture companies. Our clients can rely on our superior technologies and quality assurance system which have been developed over many years of experience in the industry.

    MORE

  • COSMETIC
    BUSINESS

    We offer sourcing, contract manufacturing and sales services of cosmetic chemicals to send beauty and moisture to customers around the world.

    MORE

  • CHEMICAL
    BUSINESS

    We supply high quality raw materials for chemicals from companies inside and outside of Japan leveraging our technologies and supply network.

    MORE

CONTACT